期刊
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
卷 265, 期 1-2, 页码 205-208出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.molcata.2006.10.004
关键词
microwave; ionic liquid; multicomponent; solvent-free; 2,4,5-trisubstituted imidazoles
The three-component synthesis of 2,4,5-trisubstituted imidazoles, a typical acid-catalyzed reaction, could be conducted successfully with good to excellent yields in a neutral ionic liquid, 1-methyl-3-heptyl-imidazolium tetrafluoroborate ([HeMIM]BF4), under solvent-free and microwaveassisted conditions. The combined merits of microwave irradiation and ionic liquid make the three-component condensation with safe operation, low pollution, rapid access to products and simple workup. (c) 2006 Elsevier B.V. All rights reserved.
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