期刊
SYNLETT
卷 -, 期 5, 页码 745-748出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2007-970762
关键词
alpha-amino phosphonates; aldehydes; amines; alkyl phosphite; bismuth nitrate pentahydrate; synthetic methods
A simple, efficient, and environmentally benign method has been developed for the synthesis of alpha-amino phosphonates through a one-pot reaction of aldehydes with amines and diethyl phosphite in the presence of bismuth nitrate pentahydrate as a catalyst. Some of the major advantages of this protocol are: good yields, the involvement of a less-expensive and non-toxic catalyst, mild and solvent-free reaction conditions and also tolerance towards other functional groups present in the substrates. Eighteen examples are described, highlighting the substrate scope of the reaction.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据