期刊
TETRAHEDRON LETTERS
卷 48, 期 12, 页码 2159-2163出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.01.105
关键词
indoles; Michael addition; pyrimidines; solvent-free reaction; multicomponent reaction
Synthesis of some novel 3-alkylated indoles via an uncatalyzed Michael addition of indoles using three components in one-pot solvent-free conditions is reported. The mechanism was established by performing the reaction in two steps. The reaction was also studied in different solvents and an important solvent effect was noticed. (c) 2007 Elsevier Ltd. All rights reserved.
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