期刊
BIOLOGICAL PSYCHOLOGY
卷 75, 期 1, 页码 68-74出版社
ELSEVIER
DOI: 10.1016/j.biopsycho.2006.12.002
关键词
blood pressure; depression; heart rate; psychological stress
资金
- MRC [MC_U130059811, MC_U130059821] Funding Source: UKRI
- Medical Research Council [MC_U130059821, MC_U130059811] Funding Source: researchfish
- Medical Research Council [MC_U130059811, MC_U130059821] Funding Source: Medline
Depression and exaggerated cardiovascular reactivity are considered risk factors for cardiovascular disease, possibly as a result of common antecedents, such as altered autonomic nervous system function. We examined the association between depressive symptomatology and cardiovascular reactions to psychological stress in 1608 adults (875 women) comprising 3 distinct age cohorts: 24-, 44-, and 63-year olds. Depression was assessed using the Hospital Anxiety and Depression Scale. Blood pressure and heart rate were measured at baseline and during the paced auditory serial arithmetic test. Depression scores were negatively associated with systolic blood pressure and heart rate reactions, after adjustment for likely confounders such as sex, cohort, occupational status, body mass index, stress task performance score, baseline cardiovascular activity, antidepressant, and antihypertensive medication. The direction of association was opposite to that which would be expected if excessive reactivity were to mediate the association between depression and cardiovascular disease outcomes or if they shared common antecedents. (c) 2006 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据