期刊
NATURE STRUCTURAL & MOLECULAR BIOLOGY
卷 14, 期 4, 页码 347-348出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb1218
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资金
- NICHD NIH HHS [P30-HD026979] Funding Source: Medline
- NIGMS NIH HHS [GM0720777] Funding Source: Medline
- NINDS NIH HHS [NS053839] Funding Source: Medline
Piwi-interacting RNAs (piRNAs) are a novel class of small RNAs that are expressed specifically and abundantly in male germ cells. Here we report that the 3' termini of piRNAs are 2'-O-methylated; this modification may have important implications for the biogenesis and function of piRNAs.
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