期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 17, 期 7, 页码 1879-1882出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2007.01.078
关键词
kobophenol A; SH-SY5Y; neuroprotection
This study examined the neuroprotective effects of kobophenol A (kob A), oligomeric stillbene, and a resveratrol tetramer. Neuronal death induced by the withdrawal of tropic support was ameliorated by kob A. The protective effect of kob A against nitrosative/oxidative or mitochondrial damages resulted in the inhibition of the ROS, intracellular calcium ion level, and mitochondrial transmembrane potential changes on SH-SY5Y cells. (c) 2007 Elsevier Ltd. All rights reserved.
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