期刊
BIOORGANIC & MEDICINAL CHEMISTRY
卷 15, 期 7, 页码 2708-2714出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2007.01.035
关键词
Marrubium velutinum; M. cylleneum; tyrosinase; flavonoids; phenylethanoid glycosides; phenolic acids
Tyrosinase is a key enzyme in the production of melanins in plants and animals. Forty-five secondary metabolites isolated from Marrubium velutinum and Marrubium cylleneum belonging to the classes of flavonoids, phenylethanoid glycosides, phenolic acids and lignan glycosides were screened for their inhibitory activity against mushroom tyrosinase. Flavonoids and phenylethanoid glycosides showed moderate inhibitory activity, while phenolic acids were less active than phenylethanoid glycosides, suggesting that both phenolic groups are important for the activity. (c) 2007 Elsevier Ltd. All rights reserved.
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