期刊
PHYTOMEDICINE
卷 14, 期 4, 页码 289-300出版社
ELSEVIER GMBH, URBAN & FISCHER VERLAG
DOI: 10.1016/j.phymed.2007.02.002
关键词
plants; botanicals; acetylcholinesterase inhibition; acetylcholine; Alzheimer's disease
Inhibition of acetylcholinesterase (AChE), the key enzyme in the breakdown of acetylcholine, is considered as a promising strategy for the treatment of neurological disorders such as Alzheimer's disease, senile dementia, ataxia and myasthenia gravis. A potential source of AChE inhibitors is certainly provided by the abundance of plants in nature. This article aims to provide a comprehensive literature survey of plants that have been tested for AChE inhibitory activity. Numerous phytoconstituents and promising plant species as AChE inhibitors are being reported in this communication. (c) 2007 Elsevier GmbH. All rights reserved.
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