期刊
NATURE NEUROSCIENCE
卷 10, 期 4, 页码 512-522出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nn1865
关键词
-
资金
- NEI NIH HHS [1R21EY017741, R21 EY017741] Funding Source: Medline
- NIDA NIH HHS [5R21DA15893, R21 DA015893] Funding Source: Medline
- NIMH NIH HHS [R21 MH066747, T32 MH019908, T32 MH19908, 1R21MH66747] Funding Source: Medline
High-level visual cortex in humans includes functionally defined regions that preferentially respond to objects, faces and places. It is unknown how these regions develop and whether their development relates to recognition memory. We used functional magnetic resonance imaging to examine the development of several functionally defined regions including object ( lateral occipital complex, LOC)-, face ('fusiform face area', FFA; superior temporal sulcus, STS)- and place ('parahippocampal place area', PPA)-selective cortices in children (ages 7 - 11), adolescents (12 - 16) and adults. Right FFA and left PPA volumes were substantially larger in adults than in children. This development occurred by expansion of FFA and PPA into surrounding cortex and was correlated with improved recognition memory for faces and places, respectively. In contrast, LOC and STS volumes and object-recognition memory remained constant across ages. Thus, the ventral stream undergoes a prolonged maturation that varies temporally across functional regions, is determined by brain region rather than stimulus category, and is correlated with the development of category-specific recognition memory.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据