Electrochemical determination of acetaminophen using a glassy carbon electrode coated with a single-wall carbon nanotube-dicetyl phosphate film

Single-wall carbon nanotubes (SWNT) were dispersed into water in the presence of dicetyl phosphate (DCP), and then a SWNT-DCP film-coated glassy carbon electrode ( GCE) was constructed. The electrochemical behavior of acetaminophen at bare GCE and SWNT-DCP modified GCE were compared, suggesting that the SWNT-DCP-modified GCE significantly enhances the oxidation peak current of acetaminophen. A sensitive and simple electrochemical method with a good linear relationship in the range of 1.0 x 10(-7) - 2.0 x 10(-5) mol L-1, was developed for the determination of acetaminophen. The detection limit is 4.0 x 10(-8) mol L-1 for 3-min accumulation. This method was successfully demonstrated with tablets.