Species-specific differences in the susceptibilities of biofilms formed by Candida bloodstream isolates to echinocandin antifungals

The echinocandin susceptibilities of bloodstream Candida isolates growing in a biofilm was investigated. Within the therapeutic range of concentrations of each drug, caspofungin and micafungin were active against biofilms formed by Candida albicans or C glabrata but not those formed by C. tropicalis or C. parapsilosis.