期刊
JOURNAL OF NATURAL PRODUCTS
卷 70, 期 4, 页码 538-543出版社
AMER CHEMICAL SOC
DOI: 10.1021/np060450q
关键词
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Four bis-piperidine alkaloids, madangamine F (1), haliclonacyclamine F (2). and arenosclerins D (3) and E (4), have been isolated from the marine sponge Pachychalina alcaloidifera and have been identified by analysis of spectroscopic data. The alkaloids displayed cytotoxic activity against different cancer cell lines. These results support the hypothesis of a common biogenetic origin for the Haplosclerida bis-piperidine and bis-pyridine alkaloids.
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