期刊
TISSUE ANTIGENS
卷 69, 期 -, 页码 150-152出版社
BLACKWELL PUBLISHING
DOI: 10.1111/j.1399-0039.2006.763_6.x
关键词
HLA-G; immune inhibition; tolerance
Human leukocyte antigen (HLA)-G is a nonclassical HLA class I molecule that has tolerogenic functions and acts on cells of both innate and adaptive immunity. The molecular mechanism leading to tolerance involves the interaction between HLA-G and inhibitory receptors that are expressed at the surface of immune cells. In this review, we will briefly summarize the key advances on the relationships between HLA-G and the immune system and their consequences in pathology.
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