Amberlist-15 as heterogeneous reusable catalyst for regioselective ring opening of epoxides with amines under mild conditions

Oxiranes undergo rapid ring-opening reaction with amines catalyzed by Amberlist-15 under mild reaction conditions. The reactions were carried out at room temperature to afford the corresponding beta-amino alcohols in excellent yields and high regioselectivity. The catalyst was recovered and reused further without loss of activity. (c) 2006 Elsevier B.V. All rights reserved.