期刊
SYNTHESIS-STUTTGART
卷 -, 期 7, 页码 1070-1076出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2007-965970
关键词
salicylihalamide; cytotoxicity; Sharpless epoxidation; metathesis
Stereoselective synthesis of the macrocyclic core of salicylihalamides A and B is described. The synthetic strategy features stereoselective iodolactonization, Sharpless asymmetric epoxidation, Mitsunobu esterification, and ring-closing metathesis.
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