期刊
CIRCULATION JOURNAL
卷 71, 期 5, 页码 661-668出版社
JAPANESE CIRCULATION SOC
DOI: 10.1253/circj.71.661
关键词
left ventricular torsion; radial strain; tissue tracking
Background The difference in the left ventricular (LV) torsion of the endo- and epicardium (Endo, Epi) with. inotropic stimulation and its relation to radial strain (RS) remain unclear. Methods and Results LV basal and apical short-axis images were recorded in 13 normal subjects at rest and during dobutamine infusion (5, 10 mu g center dot kg(-1)center dot min(-1)). A total of 8 points (anterior, lateral, posterior and septum in both Endo and Epi) were manually placed by 2-dimensional tissue tracking technique and the movement of these points during a cardiac cycle was tracked, after which the rotation angles and RS were calculated. LV torsion was defined as the net difference between the basal and apical rotations. In the LV apex, Endo-rotation increased (7.8 +/- 2.7 to 14.1 +/- 4.6 degrees, p < 0.01), whereas Epi-rotation was unchanged, with dobutamine. The apical Endorotation was significantly greater than the Epi-rotation, although no difference was seen between the Endo and Epi in the LV base throughout the study. During dobutamine infusion, the LV Endo-torsion increased (9.5 +/- 2.8 to 19.3 +/- 4.8 degrees, p < 0.01) and these values were greater than those for Epi. The apical RS increased with the dobutamine dose (39.0 +/- 9.3 to 61.9 +/- 15.5%, p < 0.01), whereas basal RS initially increased at 5 mu g center dot kg(-1)center dot min(-1), but thereafter showed no further increase at 10 mu g center dot kg(-1)center dot min(-1) of dobutamine. Conclusions Augmentation of LV rotation with inotropism was clearly observed in the apical Endo, thus causing increased LV endo-torsion and apical RS.
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