4.6 Review

Prognosis of antenatally diagnosed oligohydramnios of renal origin

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EUROPEAN JOURNAL OF PEDIATRICS
卷 166, 期 5, 页码 393-398

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SPRINGER
DOI: 10.1007/s00431-006-0368-9

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antenatal; ultrasound; renal oligohydramnios (ROH); outcome; chronic renal failure; chronic kidney disease; congenital anomalies of kidney and urinary tract (CAKUT); pulmonary hypoplasia

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Although clinical outcome data on fetuses with oligohydramnios of renal origin are scarce, prognosis is regarded as poor due to a high risk of renal dysfunction and pulmonary hypoplasia. This review aims to summarize the current knowledge and clinical experience with patients presenting antenatally with renal oligohydramnios. By reviewing the underlying mechanisms, complications, and outcome data, we hope to further improve antenatal counseling and postnatal care. We conclude that prognosis of ROH has changed in recent years. While early data before the introduction of sophisticated neonatal intensive care and renal replacement therapy indicated a poor prognosis, nowadays, a much more optimistic prognosis of children after renal oligohydramnios can be expected from the recent publications in the literature.

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