期刊
JOURNAL OF MOLECULAR EVOLUTION
卷 64, 期 5, 页码 586-590出版社
SPRINGER
DOI: 10.1007/s00239-006-0257-x
关键词
codon bias; Drosophila miranda; reduced selection
资金
- NIGMS NIH HHS [GM076007] Funding Source: Medline
Biased codon usage in many species results from a balance among mutation, weak selection, and genetic drift. Here I show that selection to maintain biased codon usage is reduced in Drosophila miranda relative to its ancestor. Analyses of mutation patterns in noncoding DNA suggest that the extent of this reduction cannot be explained by changes in mutation bias or by biased gene conversion. Low levels of variability in D. miranda relative to its sibling species, D. pseudoobscura, suggest that it has a much smaller effective population size. Reduced codon usage bias in D. miranda may thus result from the reduced efficacy of selection against newly arising mutations to unpreferred codons.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据