期刊
AMERICAN JOURNAL OF CLINICAL PATHOLOGY
卷 127, 期 5, 页码 670-686出版社
OXFORD UNIV PRESS INC
DOI: 10.1309/MTTM86UT1XFQL7RV
关键词
skin lymphoma; CD30; mycosis fungoides; dermatitis; natural killer cell
类别
Cases drawn from Session 5 of the 2005 Society for Hematopathology/European Association for Haematopathology Workshop on progress in T-cell and natural killer (NK)-cell malignancies are used as a framework to review the current classification of T-cell and NK-cell malignancies in skin. In comparison with the typical pattern and course of mycosis fungoides (MF), selected variants of MF that can be difficult to diagnose are discussed. Cutaneous CD30+ lymphoproliferative disorders are also presented in detail. Particular focus is placed on the recognition of rare but clinically more aggressive cytotoxic lymphomas in the skin. Overall, diagnostic pitfalls and new information regarding disease pathogenesis brought up by the Workshop cases are provided. In addition, a general approach to the diagnosis of cutaneous T-cell lymphomas is discussed.
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