期刊
GENETICS
卷 176, 期 1, 页码 327-342出版社
GENETICS SOCIETY AMERICA
DOI: 10.1534/genetics.106.065037
关键词
-
资金
- NIGMS NIH HHS [R01 GM060777, R01 GM050428, GM50428, GM60777, R29 GM050428] Funding Source: Medline
Longitudinal samples of DNA sequences, the DNA sequences sampled from the same population at different time points, have increasingly been used to study the evolutionary process of fast-evolving organisms, e.g., RNA Virus, in recent years. We propose in this article several methods for testing genetical isochronism or detecting significant genetical heterochronism in this type of sample. These methods can be used to determine the necessary sample size and sampling interval in experimental design or to combine genetically isochronic samples for better data analysis. We investigate the properties of these test statistics, including their powers of detecting heterochronism, assuming different evolutionary processes using simulation. The possible choices and usages of these test statistics are discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据