期刊
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
卷 618, 期 1-2, 页码 18-29出版社
ELSEVIER
DOI: 10.1016/j.mrfmmm.2006.10.006
关键词
INO80; SWR1; ATP-dependent chromatin remodeling; DNA repair; histone variant; actin; Arps; Rvb1; Rvb2; H2AZ; H2AX
资金
- NCI NIH HHS [K22 CA100017-03, K22 CA100017] Funding Source: Medline
ATP-dependent chromatin remodeling complexes contain ATPases of the Swi/Snf superfamily and alter DNA accessibility of chromatin in an ATP-dependent manner. Recently characterized INO80 and SWR1 complexes belong to a subfamily of these chromatin remodelers and are characterized by a split ATPase domain in the core ATPase subunit and the presence of Rvb proteins. INO80 and SWR1 complexes are evolutionarily conserved from yeast to human and have been implicated in transcription regulation, as well as DNA repair. The individual components, assembly patterns, and molecular mechanisms of the INO80 class of chromatin remodeling complexes are discussed in this review. (C) 2007 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据