期刊
JOURNAL OF PEDIATRIC ONCOLOGY NURSING
卷 24, 期 3, 页码 123-131出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/1043454206298693
关键词
coagulation; coagulation cascade; cell-based theory of coagulation; bleeding disorders
Although the concept of the coagulation cascade represented a significant advance in the understanding of coagulation and served for many years as a useful model, more recent clinical and experimental observations demonstrate that the cascade/waterfall hypothesis does not fully and completely reflect the events of hemostasis in vivo. The goal of this article is to review the evolution of the theories of coagulation and their proposed models to serve as a tool when reviewing the research and practice literature that was published in the context of these different theories over time.
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