期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 17, 期 9, 页码 2577-2580出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2007.02.003
关键词
phthalazine-5,8-dione; antimicrobial compounds; antifungal; fungi; substitution effects
6-Arylamino-phthalazine-5,8-diones and 6,7-bis(arylthio)-phthalazine-5,8-diones were synthesized and tested for in vitro antifungal activity against two pathogenic strains of fungi. Among those tested, many compounds showed good antifungal activity. The results suggest that phthalazine-5,8-diones would be potent antifungal agents. (c) 2007 Elsevier Ltd. All rights reserved.
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