期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 71, 期 5, 页码 1342-1344出版社
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.60725
关键词
black currant; polysaccharides; beta-galactosidase; macrophage; antitumor
A polysaccharide-rich substance isolated from black currant, named cassis polysaccharide (CAPS), was partially digested with fl-galactosidase from Aspergillus oryzae and its immunostimulatory activity was investigated. The in vitro cytokine-inducing effect of CAPS on RAW264 cells was gradually decreased along with lowering of the average MW of CAPS. In vivo, partially digested CAPS with a mean MW of approximately 20,000 showed the most potent antitumor activity against Ehrlich carcinoma in mice.
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