期刊
CANCER GENETICS AND CYTOGENETICS
卷 175, 期 1, 页码 61-64出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cancergencyto.2006.12.008
关键词
-
Loss or mutation of known tumor suppressor genes accounts for a small proportion of all breast cancers. We have recently shown that interferon regulatory factor I (IRFI) is a putative tumor suppressor gene in breast cancer. We now report that the A4396G single nucleotide polymorphism in the IRFI gene is more frequent in human breast cancer cell lines than in the general population (P = 0.01). Furthermore, A4396G is more frequently expressed in African American (black) than in European ancestry (white) subjects (n = 70 subjects; P <= 0.001), leading to a significant difference in genotype distribution between these populations (P = 0.002). (C) 2007 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据