期刊
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
卷 851, 期 1-2, 页码 186-210出版社
ELSEVIER
DOI: 10.1016/j.jchromb.2007.02.011
关键词
reviews; nitrite; peroxynitrite; 3-nitrotyrosine; N-nitrosotryptophan; ADMA
资金
- NIAID NIH HHS [R56 AI030464, R01 AI030464-15, R01 AI030464-13A1, R01 AI030464-14, R01 AI030464, R01 AI030464-16] Funding Source: Medline
This review briefly summarizes recent progress in fundamental understanding and analytical profiling of the L-arginine/nitric oxide (NO) pathway. It focuses on key analytical references of NO actions and the experimental acquisition of these references in vivo, with capillary electrophoresis (CE) and high-performance capillary electrophoresis (HPCE) comprising one of the most flexible and technologically promising analytical platform for comprehensive high-resolution profiling of NO-related metabolites. Another aim of this review is to express demands and bridge efforts of experimental biologists, medical professionals and chemical analysis-oriented scientists who strive to understand evolution and physiological roles of NO and to develop analytical methods for use in biology and medicine. (C) 2007 Elsevier B.V. All rights reserved.
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