期刊
SYNTHESIS-STUTTGART
卷 -, 期 10, 页码 1584-1586出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2007-965954
关键词
tetrahydro-4H-thiopyran-4-one; 4-thianone; heterocyclic ketone; Dieckmann cyclization; thiopyran synthesis
Tetrahydro-4H-thiopyran-4-one was prepared in >75% yield by treatment of dimethyl 3,3 '-thiobispropanoate with NaOMe (generated in situ) in THF solution and decarboxylation of the resulting metbyl tetrahydro-4-oxo-2H-thiopyran-3-carboxyl ate in refluxing 10% aqueous H2SO4. Reaction of tetrahydro-4H-thiopyran-4-one with Me3SiCI and Et3N in CHCl3 gave the corresponding trimethylsilyl enol ether in near quantitative yield. The prepared reagents are useful for the synthesis of thiopyran-containing compounds.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据