期刊
FEBS LETTERS
卷 581, 期 11, 页码 2098-2104出版社
WILEY
DOI: 10.1016/j.febslet.2007.03.019
关键词
rafts; membrane microstructure; cholesterol-facilitated; liquid-ordered
资金
- NIGMS NIH HHS [R01 GM066717, R01 GM066717-04] Funding Source: Medline
Membrane rafts are regions of increased lipid acyl chain order that differ in their lipid and protein composition from the surrounding membrane. By providing an additional level of compartmentalization they have been proposed to serve many functions in cellular signal transduction and trafficking. We will review their potential involvement in different forms of membrane traffic, explicitly excluding signalling, and discuss select aspects of the raft hypothesis in its current form. (C) 2007 Published by Elsevier B.V. on behalf of the Federation of European Biochemical Societies.
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