期刊
NATURE CHEMICAL BIOLOGY
卷 3, 期 6, 页码 321-322出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nchembio878
关键词
-
资金
- NIGMS NIH HHS [GM59907] Funding Source: Medline
Methods for introducing bioorthogonal functionalities into proteins have become central to protein engineering efforts. Here we describe a method for the site-specific introduction of aldehyde groups into recombinant proteins using the 6-amino-acid consensus sequence recognized by the formylglycine-generating enzyme. This genetically encoded 'aldehyde tag' is no larger than a His(6) tag and can be exploited for numerous protein labeling applications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据