New cytotoxic steroids from the soft coral Clavularia viridis

Ten new cytotoxic steroids, stoloniferones H-Q (1-10) were isolated from the methylene chloride solubles of the soft coral Clavularia viridis. The structures of the metabolites were elucidated on the basis of spectroscopic (IR, MS, and ID and 2D NMR) analysis and their cytotoxicity against selected cancer cells was measured in vitro. (c) 2007 Elsevier Inc. All rights reserved.