期刊
BRITISH JOURNAL OF PSYCHIATRY
卷 190, 期 -, 页码 533-534出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1192/bjp.bp.106.028019
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- Wellcome Trust Funding Source: Medline
The place of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression remains unclear. In this sham-controlled study we determined the efficacy and acceptability of fast, left frontal rTMS given three times a week over 4-6 weeks to 29 patients with depression (79% treatment-resistant). The procedure was generally well tolerated and more effective than sham treatment (55 v 7% responding, P < 0.05), with improvement maintained to 12 weeks. This therapy could be a useful addition to available treatments but further research is needed to determine the optimum treatment parameters.
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