期刊
BIOTECHNOLOGY AND BIOENGINEERING
卷 97, 期 2, 页码 207-213出版社
WILEY
DOI: 10.1002/bit.21411
关键词
protein structure prediction; protein folding; computational methods
This review presents the advances in protein structure prediction from the computational methods perspective. The approaches are classified into four major categories: comparative modeling, fold recognition, first principles methods that employ database information, and first principles methods without database information. Important advances along with current limitations and challenges are presented.
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