期刊
TRANSPLANTATION PROCEEDINGS
卷 39, 期 5, 页码 1526-1529出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.transproceed.2007.03.066
关键词
-
Purpose. Following implantation into adult recipients, living donor liver grafts usually undergo liver regeneration. This regeneration process may provoke the growth of occult hepatocellular carcinoma (HCC) cells in the recipient body. To assess the risk of HCC recurrence, we analyzed the influence of graft-recipient weight ratio (GRWR). Methods. The 181 recipients with HCC within the University of California at San Francisco (UCSF) criteria were divided into four groups according to GRWR: low GRWR (< 0.8; n = 30), mid GRWR (0.8-1.0; n = 65), high GRWR (> 1.0; n = 64), and whole liver graft group (> 1.5; n = 22). Results. There were no differences in overall patient survival (P = .105) and recurrence-free survival (P = .406) among these four groups. GRWR < 0.8 was not a significant risk factor for HCC recurrence. Similar outcomes were obtained in HCC patients who met the Milan criteria (n = 170). Conclusions. We think that small living donor liver graft and subsequent liver regeneration do not increase the risk of posttransplant HCC recurrence when HCC is within the Milan or UCSF criteria.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据