期刊
PEDIATRIC INFECTIOUS DISEASE JOURNAL
卷 26, 期 6, 页码 542-544出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/INF.0b013e31803994a0
关键词
Epstein-Barr virus; influenza-associated encephalopathy; MMP-9; respiratory syncytial virus; TIMP-1
Matrix metalloproteinase-9 (MMP-9) and tissue inhibitors of metalloprotemases 1 (TIMP-1) play important roles in the function of the blood-brain barrier. Serum MMP-9 and TIMP-1 concentrations were determined in influenza virus infection with or without neurologic complications. Our results suggest that an imbalance between MMP-9 and TIMP-1 damages the blood-brain barrier and promotes febrile seizure or encephalopathy in influenza virus infection.
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