期刊
JOURNAL OF MEDICINAL FOOD
卷 10, 期 2, 页码 213-217出版社
MARY ANN LIEBERT, INC
DOI: 10.1089/jmf.2006.290
关键词
antioxidant; insulin resistance; peroxisome proliferator-activated receptor-gamma; pomegranate; triterpene
The current diabetes epidemic is a global concern with readily available effective therapies or preventative measures in demand. One natural product with such potential is the pomegranate (Punica granatum), with hypoglycemic activity noted from its flowers, seeds, and juice in canons of the traditional folk medicines of India. The mechanisms for such effects are largely unknown, though recent research suggests pomegranate flowers and juice may prevent diabetic sequelae via peroxisome proliferator-activated receptor-gamma binding and nitric oxide production. Pomegranate compounds associated with antidiabetic effects include oleanolic, ursolic, and gallic acids. Pomegranate fractions and their active compounds hold potentiial and are worthy of further investigation as safe and effective medical treatments for diabetes mellitus and its pathological consequences.
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