期刊
PHYSICAL REVIEW LETTERS
卷 98, 期 22, 页码 -出版社
AMER PHYSICAL SOC
DOI: 10.1103/PhysRevLett.98.228301
关键词
-
We observe the phenomenon of stochastic resonant signaling in signal amplification enzyme cascades, where certain optimal reaction rates minimize the average threshold-crossing time. We develop a new analytical technique to obtain the mean first passage time, based on a novel decomposition of the master equation. Our analytical results are in good agreement with the exact numerical simulations. We demonstrate that resonant behavior may be a ubiquitous phenomenon in stochastic threshold crossing in cell signaling. The physical principles behind this phenomenon are elucidated.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据