期刊
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
卷 27, 期 5, 页码 589-594出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.iae.0000249386.63482.05
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Purpose: To identify the tomographic features of the branching vascular networks in patients with polypoidal choroidal vasculopathy (PCV). Methods: We prospectively performed third -generation optical coherence tomography (OCT) and fluorescein angiography for 44 eyes of 42 patients (mean age SID, 67.1 +/- 9.1 years) with PCV. All eyes had branching vascular networks and polypoidal lesions that were confirmed by indocyanine green angiography. Results: OCT showed double reflective layers that consisted of retinal pigment epithelium (RPE) and another highly reflective layer beneath the RPE (double-layer sign) in the area of the branching network vessels in 26 (59%) of 44 eyes. The remaining 18 eyes had no double-layer sign, but 17 (94%) of 18 eyes had a slightly elevated RPE. A serous retinal detachment was present in 23 (88%) of 26 eyes with a double-layer sign, while only 1 (6%) of 18 eyes without the sign had a serous retinal detachment. Conclusions: In PCV, the double-layer sign is seen frequently in the area of the network vessels, particularly in eyes with a serous retinal detachment. The sign may reflect fluid accumulation between RPE and Bruch membrane resulting from leakage from the network of abnormal vessels.
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