期刊
ANALYTICAL LETTERS
卷 45, 期 11, 页码 1347-1364出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/00032719.2012.675493
关键词
Immunoassay; Multi-analyte immunoassay; Pesticide
The current trend of pesticide immunoassay is developing multi-analyte immunoassays, that is, more than one target can be detected per test. In this mini-review, the strategies to achieve multi-analyte immunoassays, which include multi-antibody strategy, broad-specificity antibody strategy, and others, are briefly introduced. In addition, the recent developments of multi-analyte immunoassays for pesticides were summarized. At last, we give a future outlook of this area, which includes rational design generic hapten with the assist of computer-assisted molecular modeling (CAMM), further improving the properties of broad-specificity antibody by recombinant antibody (rAb) technology and developing a noncompetitive immunoassay format.
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