期刊
ANALYTICAL LETTERS
卷 45, 期 9, 页码 986-992出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/00032719.2012.670784
关键词
Aptamer; Biosensor; Impedance; Nano-porous silicon; Tetracycline
资金
- Ministry of Science and Technology of the People's Republic of China [2009GJA10047]
- Tianjin Municipal Science and Technology Commission [09ZCZDSFO4200]
- Tianjin University of Science and Technology
A novel aptamer nano-porous silicon (PS) biosensor was investigated for the rapid determination of tetracyclines. Electrochemical impedance spectroscopy (EIS) was used to analyze the behavior of the sensor. The specific binding of tetracycline to the aptamer biosensor led to a decrease in impedance. The corresponding impedance spectra (Nyquist plots) were obtained when serial concentrations of tetracycline were added into the system. An equivalent electrical circuit was used to fit the impedance data. The linear range of the sensor was 2.1-62.4 nM.
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