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Opinion - Pathogen profiling for disease management and surveillance

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NATURE REVIEWS MICROBIOLOGY
卷 5, 期 6, 页码 464-470

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NATURE PUBLISHING GROUP
DOI: 10.1038/nrmicro1656

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The usefulness of rapid pathogen genotyping is widely recognized, but its effective interpretation and application requires integration into clinical and public health decision-making. How can pathogen genotyping data best be translated to inform disease management and surveillance? Pathogen profiling integrates microbial genomics data into communicable disease control by consolidating phenotypic identity-based methods with DNA microarrays, proteomics, metabolomics and sequence-based typing. Sharing data on pathogen profiles should facilitate our understanding of transmission patterns and the dynamics of epidemics.

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