期刊
PEDIATRIC NEPHROLOGY
卷 22, 期 6, 页码 893-898出版社
SPRINGER
DOI: 10.1007/s00467-006-0427-5
关键词
nephrotic syndrome; rituximab; child
We each have nephrotic patients who become steroid dependent and in whom multiple immunosuppressive agents are employed. There is a need to balance possible therapeutic benefits with drug toxicity. This case report describes such a patient, who has suffered from nephrotic syndrome for over 11 years and had become resistant to the usual therapies. He was therefore given a single dose of the anti-CD20 drug rituximab, to which he showed a prompt response, leaving him free of proteinuria for the past 10 months.
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