期刊
ANALYTICAL LETTERS
卷 42, 期 3, 页码 536-554出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/00032710802677084
关键词
Biological samples; molecularly imprinted polymer; monolithic stationary phase; propranolol
资金
- National Natural Science Foundation of China [30672551]
A propranolol molecule-imprinted monolithic stationary phase (MIMSP) was synthesized by in situ technique. The recognition mechanism of the polymers and the influences of some chromatographic conditions were examined by high-performance liquid chromatography (HPLC). The imprinted polymers showed much higher selectivity for -blockers than the nonimprinted polymers (NIPs) did, which proves the successful preparation of propranolol-imprinted polymers by using an in situ technique. Then, this technique was used to prepare a molecularly imprinted polymer solid-phase extraction column to concentrate propranolol from biological samples. The results showed that the imprinted solid-phase extraction column could selectively enrich and purify propranolol from biological samples, such as plasma.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据