期刊
ANALYTICAL CHEMISTRY
卷 86, 期 18, 页码 9036-9041出版社
AMER CHEMICAL SOC
DOI: 10.1021/ac5015854
关键词
-
资金
- HDTRA [1-10-1-0044]
- Department of Chemistry University of Pittsburgh
We fabricated a two-dimensional (2-D) photonic crystal lectin sensing material that utilizes light diffraction from a 2-D colloidal array attached to the surface of a hydrogel that contains mannose carbohydrate groups. Lectin-carbohydrate interactions create hydrogel cross-links that shrink the hydrogel volume and decrease the 2-D particle spacing. This mannose containing 2-D photonic crystal sensor detects Concanavalin A (Con A) through shifts in the 2-D diffraction wavelength. Con A concentrations can be determined by measuring the diffracted wavelength or visually determined from the change in the sensor diffraction color. The concentrations are easily monitored by measuring the 2-D array Debye ring diameter. Our observed detection limit for Con A is 0.02 mg/mL (0.7 mu M). The 2-D photonic crystal sensors are completely reversible and can monitor Con A solution concentration changes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据