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Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production
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Interleukin-27 Priming of T Cells Controls IL-17 Production In trans via Induction of the Ligand PD-L1
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Novel IL27p28/IL12p40 Cytokine Suppressed Experimental Autoimmune Uveitis by Inhibiting Autoreactive Th1/Th17 Cells and Promoting Expansion of Regulatory T Cells
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Local Expression of Interleukin-27 Ameliorates Collagen-Induced Arthritis
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IL-27 increases the proliferation and effector functions of human naive CD8(+) T lymphocytes and promotes their development into Tc1 cells
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IL-27 promotes T cell-dependent colitis through multiple mechanisms
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A Role for IL-27 in Limiting T Regulatory Cell Populations
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Interleukin-27-Mediated Suppression of Human Th17 Cells Is Associated with Activation of STAT1 and Suppressor of Cytokine Signaling Protein 1
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A Pivotal Role for Interleukin-27 in CD8(+) T Cell Functions and Generation of Cytotoxic T Lymphocytes
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IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells
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The secreted form of p28 subunit of interleukin (IL)-27 inhibits biological functions of IL-27 and suppresses anti-allogeneic immune responses
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Differential Effect of IL-27 on Developing versus Committed Th17 Cells
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Immunologic and Therapeutic Synergy of IL-27 and IL-2: Enhancement of T Cell Sensitization, Tumor-Specific CTL Reactivity and Complete Regression of Disseminated Neuroblastoma Metastases in the Liver and Bone Marrow
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c-Maf Regulates IL-10 Expression during Th17 Polarization
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IL-27 Blocks RORc Expression to Inhibit Lineage Commitment of Th17 Cells
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Bcl6 Mediates the Development of T Follicular Helper Cells
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Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor α (WSX-1)
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Interleukin 27 attenuates collagen-induced arthritis
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Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
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Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
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A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells
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Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells
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IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways
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Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
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IL-27 suppresses CD28-medicated IL-2 production through suppressor of cytokine signaling 3
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IL-27 limits IL-2 production during Th1 differentiation
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Membranous glomerulonephritis development with Th2-type immune deviations in MRL/lpr mice deficient for IL-27 receptor (WSX-1)
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Augmentation of effector CD8+ T cell generation with enhanced granzyme B expression by IL-27
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Impaired Th1 responses in mice deficient in Epstein-Barr virus-induced gene 3 and challenged with physiological doses of Leishmania major
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An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells
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The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity
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IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms
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Cutting edge: Role of IL-27/WSX-1 signaling for induction of T-Bet through activation of STAT1 during initial Th1 commitment
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The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection
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IL-27, a heterodimeric cytokine composed of EB13 and p28 protein, induces proliferation of naive CD4+ T cells
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