4.8 Article

SplicePort - An interactive splice-site analysis tool

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NUCLEIC ACIDS RESEARCH
卷 35, 期 -, 页码 W285-W291

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OXFORD UNIV PRESS
DOI: 10.1093/nar/gkm407

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SplicePort is a web-based tool for spliceanalysis that allows the user to make splicepredictions for submitted sequences. In the user can also browse the rich catalog of that underlies these predictions, and which we found capable of providing high accuracy on human splice sites. Feature is optimized for human splice sites, but the features are likely to be predictive for mammals as well. With our interactive browsing and visualization tool, the user can and explore subsets of features used in spliceprediction (either the features that account for classification of a specific input sequence or complete collection of features). Selected sets can be searched, ranked or displayed The user can group features into clusters frequency plot WebLogos can be generated each cluster. The user can browse the clusters and their contributing elements, for new interesting signals, or can validate observed signals. The SplicePort server can be accessed athttp://www.cs.umd.projects/SplicePort and http://www.spliceport.org.

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