期刊
ANALYTICAL CHEMISTRY
卷 84, 期 15, 页码 6288-6292出版社
AMER CHEMICAL SOC
DOI: 10.1021/ac300207r
关键词
-
资金
- National Natural Science Foundation of China [90813011, 21172272, 81001400]
- International S&T Cooperation Program of China [2010DFA34630]
The rapid and convenient method for identification of all kinds of G-quadruplex is highly desirable. In the present study, a novel colorimetric indicator for a vast variety of G-quadruplex was designed and synthesized on the basis of thiazole orange and isaindigotone skeleton. Its distinct color change enables label-free visual detection of G-quadruplexes, which is due to the disassembly of dye H-aggregates to monomers. This specific detection of G-quadruplex arises from its end-stacking interaction with G-quartet. On the basis of this universal indicator, a facile approach for large-scale identification of G-quadruplex was developed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据