期刊
ANALYTICAL CHEMISTRY
卷 84, 期 6, 页码 2883-2891出版社
AMER CHEMICAL SOC
DOI: 10.1021/ac203434x
关键词
-
资金
- Bill and Melinda Gates Foundation [51308]
- DARPA through the MF3Micro/nano Fluidics Fundamentals Focus Center
- Natural Sciences and Engineering Research Council (NSERC) of Canada
- NSF
- Damon Runyon Cancer Research Foundation [DRG-1805-04]
- NIH Ruth L. Kirschstein NRSA
This paper describes a paper-based microfluidic device that measures two enzymatic markers of liver function (alkaline phosphatase, ALP, and aspartate aminotransferase, AST) and total serum protein. A device consists of four components: (i) a top plastic sheet, (ii) a filter membrane, (iii) a patterned paper chip containing the reagents necessary for analysis, and (iv) a bottom plastic sheet. The device performs both the sample preparation (separating blood plasma from erythrocytes) and the assays; it also enables both qualitative and quantitative analysis of data. The data obtained from the paper-microfluidic devices show standard deviations in calibration runs and spiked standards that are acceptable for routine clinical use. This device illustrates a type of test useable for a range of assays in resource-poor settings.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据