期刊
ANALYTICAL CHEMISTRY
卷 84, 期 15, 页码 6630-6637出版社
AMER CHEMICAL SOC
DOI: 10.1021/ac300999v
关键词
-
资金
- SNCF [20735001, 20628506]
- SNF [SNF 20PA21_121570/1]
- Deutsche Forschungsgemeinschaft [Wi 1617/10]
This manuscript presents a push-pull electrochemical scanner able to image reactivity of initially dry surfaces by scanning electrochemical microscopy (SECM) and to probe molecules present or generated at the surface by mass spectrometry (MS). The proof-of-concept is demonstrated by coupling SECM with matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) for imaging latent human fingerprints, which had been in contact with picric acid used here as a model explosive. The push pull electrochemical scanner has also been coupled with electrospray ionization mass spectrometry (ESI-MS) to assay the activity of surface spotted enzymes. These experimental studies are complemented by 3D finite element simulations solving Navier- Stokes and diffusion-convection differential equations to optimize the coupling between SECM imaging and mass spectrometry detection.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据