期刊
JOURNAL OF OPTICS A-PURE AND APPLIED OPTICS
卷 9, 期 7, 页码 699-703出版社
IOP Publishing Ltd
DOI: 10.1088/1464-4258/9/7/022
关键词
localized surface plasmon resonance; biosensor; Ag nanostructured film
类别
Ag nanostructured films fabricated by the reduction of sputtered AgOx thin films are shown to exhibit a strong localized surface plasmon resonance (LSPR) at wavelengths around 370 nm. The spectral position of the LSPR, defined as the wavelength of minimal reflectance, shifts linearly depending on the refractive index n of the surrounding medium in a range of n = 1.0-1.5. By the immobilization of biotin molecules at the Ag surface, events of binding between the immobilized biotin and solution-phase streptavidin were probed for streptavidin concentrations in a range of 16 nM-8 mu M. From the sigmoidal fitting of the data, the surface-confined binding affinity constant was estimated as Ka, surf = 3.0 x 106 M-1. These results experimentally demonstrate the great potential of the Ag nanostructured films for application as cost-effective LSPR biosensors.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据