期刊
ANALYTICAL CHEMISTRY
卷 84, 期 15, 页码 6317-6320出版社
AMER CHEMICAL SOC
DOI: 10.1021/ac301541r
关键词
-
资金
- NIGMS [GM 067193-09, GM 103493-10]
- NCI [CA 155252]
- Northwestern University Physical Sciences Oncology Center [CA 143869]
- Chicago Biomedical Consortium
Differential ion mobility spectrometry (field asymmetric waveform ion mobility spectrometry (FAIMS)) is emerging as a broadly useful tool for separation of isomeric modified peptides with post-translational modifications (PTMs) attached to alternative residues. Such separations were anticipated to become more challenging for smaller PTMs and longer peptides. Here, we show that FAIMS can fully resolve localization variants involving a PTM as minuscule as methylation, even for larger peptides in the middle-down range.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据